| Booth School of Business | business school | — | 1898 |
| Booz Allen Hamilton | business, public company | Tysons | 1914 |
| BorgWarner | business, enterprise, public company | Auburn Hills | 1880 |
| Boston Athenæum | nonprofit organization, art museum, rare book library, library | Boston | 1850 |
| Boston Beer Company | brewery, public company | Boston | 1985 |
| Boston Dynamics | business | Waltham | November 6, 1992 |
| Boston Latin School | magnet school | — | April 23, 1635 |
| Bowling Green State University | public educational institution of the United States, open-access publisher, public university | — | 1910 |
| Box | website, business, enterprise, public company | Redwood City | May 2009 |
| Bradley University | private not-for-profit educational institution, private university | — | 1897 |
| Branded Entertainment Network | photo library, advertising agency, photo agency | Seattle, Los Angeles | 1989 |
| Brandywine Productions | film production company | United States | 1960 |
| Braniff International Airways | airline | Dallas, Oklahoma City | 1928 |
| Brewster Aeronautical Corporation | aerospace manufacturer | — | 1932 |
| Brigham Young University–Hawaii | private not-for-profit educational institution, university | — | 1955 |
| Brigham Young University–Idaho | private not-for-profit educational institution, university | Rexburg | — |
| Broadcast Music, Inc. | copyright collective, performing rights organization, business, company | Manhattan | 1939 |
| Broadcom | business, enterprise | Irvine | August 1991 |
| Brocade Communications Systems | business, subsidiary company, enterprise, public company | San Jose | 1995 |
| Brooklyn College | college, public educational institution of the United States | Brooklyn | 1930 |
| Brooklyn Public Library | library network, public library | — | 1896 |
| Brown & Williamson | business, enterprise | Louisville | 1894 |
| Brown-Forman | organization, business, public company | Louisville | 1870 |
| Brushfire Records | record label, record company | Los Angeles | 2002 |
| Bucyrus International | business, enterprise, public company | South Milwaukee | 1880 |
| Budd Company | business, aerospace manufacturer | Philadelphia | 1912 |
| Budget Rent a Car | business | Chicago, Parsippany-Troy Hills | 1958 |
| Build-A-Bear Workshop | business, public company | St. Louis | 1997 |
| Bunge Limited | business, enterprise, public company | Hamilton, White Plains | 1818 |
| Bureau of Engraving and Printing | building of public administration, United States federal agency, printing company | Washington, D.C. | August 29, 1862 |
| Burger Chef | business | Indianapolis | 1954 |
| Burlington | business, public company | Florence | 1972 |
| Burlington Northern Railroad | railway company | Fort Worth, Saint Paul, Seattle | March 2, 1970 |
| Burt's Bees | business, subsidiary company | Durham | 1984 |
| Burton Snowboards | business | Burlington | 1977 |
| Butler University | private not-for-profit educational institution, private university | — | 1855 |
| C. F. Martin & Company | business | Nazareth | 1833 |
| C. H. Robinson Worldwide | business, public company | Eden Prairie | 1905 |
| Cabot Corporation | business, public company | Boston | 1882 |
| CACI | corporation, public company | Arlington County | July 17, 1962 |
| Cadence Design Systems | organization, business, enterprise, public company | San Jose | 1988 |
| Calico | business | San Francisco | September 18, 2013 |
| California Academy of Sciences | planetarium, nonprofit organization, natural history museum, public aquarium, academy of sciences, learned society | San Francisco | 1853 |
| California College of the Arts | private not-for-profit educational institution, art academy, university | Oakland, San Francisco | 1907 |
| California Institute of the Arts | private not-for-profit educational institution, film school, art academy, private university | — | 1961 |
| California Pizza Kitchen | restaurant chain, pizzeria chain, public company | Los Angeles | 1985 |
| California State University | state university system, university | Long Beach | 1857 |
| California State University, Bakersfield | public educational institution of the United States, university | Bakersfield | 1965 |