| University of Dayton | private not-for-profit educational institution, university | — | 1850 |
| University of Denver | research university, private not-for-profit educational institution, private university | Denver | 1864 |
| University of Dubuque | private not-for-profit educational institution, school, university | — | 1852 |
| University of Georgia | university | Old North Campus | 1785 |
| University of Guam | university, land-grant university | — | 1952 |
| University of Hawaii Press | open-access publisher, university press | Honolulu | 1947 |
| University of Hawaiʻi at Mānoa | public educational institution of the United States, land-grant university, public university | — | 1907 |
| University of Illinois Chicago | public educational institution of the United States, open-access publisher, public university | — | January 1983 |
| University of Illinois Springfield | public educational institution of the United States, university | — | 1969 |
| University of Iowa | public educational institution of the United States, public research university | Iowa City | 1847 |
| University of Kentucky | public educational institution of the United States, open-access publisher, land-grant university, public university | Lexington | 1865 |
| University of Louisiana at Lafayette | public educational institution of the United States, university | Lafayette | 1900 |
| University of Louisville | public educational institution of the United States, public research university | Louisville | 1798 |
| University of Maine | public educational institution of the United States, land-grant university, public research university | — | 1865 |
| University of Maryland | publishing house, public educational institution of the United States, land-grant university, public research university | College Park | 1856 |
| University of Massachusetts | state university system | Boston | 1863 |
| University of Massachusetts Boston | public educational institution of the United States, university | Dorchester | 1964 |
| University of Massachusetts Lowell | public educational institution of the United States, public university | Lowell | 1975 |
| University of Memphis | public educational institution of the United States, public research university | — | 1912 |
| University of Miami | private not-for-profit educational institution, university | Coral Gables | 1925 |
| University of Michigan Law School | law school | — | 1859 |
| University of Michigan Press | open-access publisher, university press | Ann Arbor | 1930 |
| University of Michigan–Flint | public educational institution of the United States, university | — | 1956 |
| University of Minnesota | production company, public educational institution of the United States, open-access publisher, land-grant university, public research university | Minneapolis | 1851 |
| University of Missouri–Kansas City | public educational institution of the United States, public university | — | 1933 |
| University of Nebraska Omaha | public educational institution of the United States, public university | — | 1908 |
| University of Nevada, Las Vegas | public educational institution of the United States, public research university | Las Vegas | September 10, 1957 |
| University of Nevada, Reno | public educational institution of the United States, land-grant university, public research university | Reno | 1874 |
| University of North Carolina at Asheville | liberal arts college, public educational institution of the United States | Asheville | 1927 |
| University of North Carolina at Charlotte | public educational institution of the United States, public research university | — | 1946 |
| University of North Carolina at Greensboro | public educational institution of the United States, university, open-access publisher | Greensboro | 1891 |
| University of North Carolina Press | nonprofit organization, open-access publisher, university press | Chapel Hill | 1922 |
| University of North Carolina Wilmington | public educational institution of the United States, public university | Wilmington | 1947 |
| University of North Florida | public educational institution of the United States, university | — | 1969 |
| University of Notre Dame | private not-for-profit educational institution, open-access publisher, Catholic university, private university, academic publisher | — | November 26, 1842 |
| University of Oklahoma | public educational institution of the United States, university, public research university | Norman | 1890 |
| University of Oregon | research university, public educational institution of the United States, public university | Eugene | 1876 |
| University of Phoenix | private for-profit educational institution, university | Phoenix | 1976 |
| University of Puerto Rico | public university | — | 1903 |
| University of Puget Sound | liberal arts college, Colleges That Change Lives, private not-for-profit educational institution | Tacoma | 1888 |
| University of Rhode Island | research university, public educational institution of the United States, open-access publisher, land-grant university, public university | Kingston | 1892 |
| University of Richmond | private not-for-profit educational institution, university | Richmond | 1830 |
| University of Rochester | private not-for-profit educational institution, university | Rochester | 1850 |
| University of San Francisco | publishing house, private not-for-profit educational institution, university, open-access publisher | San Francisco | 1855 |
| University of South Carolina | research university, public educational institution of the United States, public university | — | 1801 |
| University of South Florida | public educational institution of the United States, open-access publisher, public university | — | 1956 |
| University of Southern Mississippi | public educational institution of the United States, open-access publisher, public university | — | March 30, 1910 |
| University of St. Thomas | private not-for-profit educational institution, private university | Saint Paul | 1885 |