| New World Interactive | video game developer | Denver | 2010 |
| Nicalis | video game developer | Santa Ana | 2007 |
| Nightdive Studios | video game publisher, video game developer | Vancouver | 2013 |
| NovaLogic | video game developer | Agoura Hills | 1985 |
| NStigate Games | video game developer | Marin County | March 1998 |
| Obsidian Entertainment | video game publisher, video game developer, business | Irvine | June 12, 2003 |
| Oddworld Inhabitants | video game developer | Berkeley | 1994 |
| Panic | video game publisher, video game developer, business | Portland, Oregon | — |
| Petroglyph Games | video game publisher, video game developer | Las Vegas | April 1, 2003 |
| Pi Studios | video game developer | Houston | 2002 |
| Razer Inc. | privately held company, business, public company | George Town, Singapore, Carlsbad, Irvine, San Francisco | 1998 |
| Renegade Kid | video game publisher, video game developer | Austin | 2007 |
| Respawn Entertainment | video game developer | Sherman Oaks, Los Angeles | 2010 |
| Rockstar Games | video game publisher | New York City | December 1998 |
| Saber Interactive | video game developer | Fort Lauderdale, Minsk, Sundsvall, Porto, Millburn, Community of Madrid, Saint Petersburg, Florida | 2001 |
| Santa Monica Studio | video game developer | Playa Vista | 1999 |
| Sanzaru Games | video game developer | Foster City, California | 2007 |
| Shaba Games | business | San Francisco | 1997 |
| Shiny Entertainment | video game developer, business | Laguna Beach, Newport Beach | 1993 |
| Sledgehammer Games | video game developer | Foster City | 2009 |
| Sony Imagesoft | business | Los Angeles | 1989 |
| Spectrum HoloByte | video game developer | Alameda | 1983 |
| Strategic Simulations | video game publisher, video game developer, business, enterprise | Sunnyvale | 1979 |
| Sucker Punch Productions | video game developer | Bellevue | October 1997 |
| Thatgamecompany | video game developer | Santa Monica | May 15, 2006 |
| The 3DO Company | video game publisher, video game console manufacturer, video game developer | Redwood City | September 12, 1991 |
| The Collective | video game developer | Newport Beach | 1997 |
| The Learning Company | video game developer | Cedar Rapids, San Francisco | 1980 |
| THQ | video game publisher, video game developer, public company | Agoura Hills, California | 1990 |
| Tiger Electronics | business, subsidiary company | Vernon Hills | 1978 |
| Tilted Mill Entertainment | video game developer | Framingham | 2001 |
| Toys for Bob | video game developer | Novato | 1989 |
| Undead Labs | business | Seattle | November 23, 2009 |
| Valve Corporation | computer manufacturer, software company, video game publisher, video game developer | Bellevue | 1996 |
| Vivendi Games | video game developer, business | Los Angeles | February 21, 1996 |
| Volition | video game developer | Champaign | November 1996 |
| Wargaming Seattle | video game developer | Redmond | — |
| Warner Bros. Entertainment | film production company, entertainment company | Burbank | April 4, 1923 |
| WayForward Technologies | video game publisher, video game developer | Valencia | 1990 |
| WB Games Boston | video game developer | Westwood | 1994 |
| Westwood Studios | video game developer, business | Las Vegas | 1992 |
| Yacht Club Games | video game developer | Valencia | 2011 |
| ZeniMax Media | holding company | Rockville | May 26, 1999 |
| Zombie Studios | video game developer | New-York Tribune | 1994 |