| American Motors Corporation | Kenosha | 1954 |
| Baker Motor Vehicle | Cleveland | 1899 |
| Canoo | Torrance | 2017 |
| Carroll Shelby International | Enterprise | August 17, 1962 |
| Cartercar | Pontiac | 1905 |
| Checker Motors Corporation | Kalamazoo | 1922 |
| DeLorean Motor Company | Detroit | October 24, 1975 |
| Detroit Electric Car Company | Detroit | 1907 |
| Diamond-Star Motors | — | October 1985 |
| Durant Motors | Lansing | 1921 |
| Eagle | — | 1987 |
| Faraday Future | Gardena | 2014 |
| Ford Motor Company | Dearborn | June 16, 1903 |
| Global Electric Motorcars | Fargo | 1992 |
| Henry Ford Company | Detroit | 1901 |
| Hudson Motor Car Company | Detroit | 1909 |
| Hupmobile | Detroit | 1909 |
| Kaiser Jeep | Toledo | 1953 |
| Kaiser Motors | Ypsilanti | 1945 |
| LaSalle | Detroit | 1927 |
| Lincoln Motor Company | Dearborn | 1917 |
| Panoz Auto Development | Hoschton | 1989 |
| Peerless | Cleveland | 1900 |
| Polaris | Medina | 1954 |
| Pope Manufacturing Company | Hartford | 1876 |
| Ram Trucks | Auburn Hills | 2010 |
| Rickenbacker | Detroit | 1921 |
| Rivian Automotive | Detroit | June 2009 |
| Scripps-Booth | Detroit | 1913 |
| Scuderia Cameron Glickenhaus | Sleepy Hollow | 2004 |
| Stanley Motor Carriage Company | Newton | 1902 |
| Stellantis North America | Chrysler Headquarters and Technology Center | April 28, 2009 |
| Studebaker | South Bend | 1852 |
| Studebaker-Packard Corporation | Detroit | 1954 |
| Thomas Built Buses | High Point | 1972 |
| VLF Automotive | Rochester | 2015 |
| Willys | Toledo | 1908 |