| Aldus | business | Seattle | February 1, 1984 |
| Altair Engineering | business, public company | Troy | 1985 |
| Bentley Systems | business, public company | Exton | 1984 |
| BMC Software | business, enterprise | Houston | 1980 |
| Cadence Design Systems | organization, business, enterprise, public company | San Jose | 1988 |
| CodeGear | business, enterprise | Scotts Valley, California | 2006 |
| Databricks | software company, business | San Francisco | 2013 |
| DataStax | business | Santa Clara | April 2010 |
| Dell | business, enterprise, public company | Round Rock | September 7, 2016 |
| Dell EMC | business, enterprise, public company | Hopkinton | August 1979 |
| E-mu Systems | business, musical instrument manufacturing company | Scotts Valley | 1971 |
| Epicor | business, enterprise | Austin, Irvine | 1972 |
| FactSet | business, public company | Norwalk | 1978 |
| Firebase | service on Internet, software framework, business | San Francisco | 2010 |
| Frogdesign | organization, business | San Francisco | 1969 |
| GoTo | software company, enterprise, public company | Boston | 2003 |
| Hewlett Packard Enterprise | computer manufacturer, software company, business, enterprise | Spring | November 1, 2015 |
| Hewlett-Packard | computer manufacturer, software company, camera manufacturer, business, enterprise | Palo Alto | July 2, 1939 |
| HubSpot | business, software development | Cambridge | 2006 |
| IBM | software company, multinational corporation, technology company, professional services firm, organization, business, enterprise, public company | Armonk | June 16, 1911 |
| Macromedia | business, enterprise | San Francisco | February 25, 1992 |
| Narus | business, software | Sunnyvale | 1997 |
| NeXT | business, enterprise | Palo Alto, Redwood City | June 20, 1985 |
| Open Invention Network | business, enterprise | Durham, New York City | November 10, 2005 |
| Panic | video game publisher, video game developer, business | Portland, Oregon | — |
| Pegasystems | business, public company | Cambridge | 1983 |
| Perforce Zend | brand, business, enterprise | Minneapolis | 1999 |
| Quest Software | business | Aliso Viejo | 1987 |
| Real3D | business | Orlando | 1986 |
| RealNetworks | privately held company, business, enterprise | Seattle | 1993 |
| Red Hat | business, enterprise, public company | Raleigh | March 27, 1993 |
| Salesforce | software company, technology company, software developer, business, enterprise, public company | Salesforce Tower, San Francisco | February 3, 1999 |
| Semrush | brand, business, public company | Boston | August 3, 2008 |
| SoundHound | music recognition software, enterprise, public company | Santa Clara | September 2005 |
| Strategy | software company, business, public company | Tysons | 1989 |
| Tibco Software | business, enterprise, public company | Palo Alto | 1997 |
| Twilio | website, business, company, public company | San Francisco | 2008 |
| Ximian | business, enterprise | Boston | October 19, 1999 |