| American Statistical Association | production company, nonprofit organization, open-access publisher, scientific society | November 27, 1839 |
| Arctic Coal Company | mining company | 1906 |
| AT&T Corporation | concern, business, enterprise | March 3, 1885 |
| Au Bon Pain | business | 1978 |
| Bain & Company | management consulting company | 1973 |
| Berklee College of Music | private not-for-profit educational institution, college of music, private university | 1945 |
| Boston Athenæum | nonprofit organization, art museum, rare book library, library | 1850 |
| Boston Beer Company | brewery, public company | 1985 |
| Cabot Corporation | business, public company | 1882 |
| Circle | dot-com company, business | October 2013 |
| Credo Reference | business | 1999 |
| Da Capo Press | publishing house | 1964 |
| Emerson College | private not-for-profit educational institution, university | 1880 |
| Federal Reserve Bank of Boston | organization, Federal Reserve Bank | October 1914 |
| Fenway Sports Group | business, enterprise | 2001 |
| Fidelity Investments | business, enterprise | 1946 |
| GoTo | software company, enterprise, public company | 2003 |
| Harvard Business School | business school, organization | 1908 |
| Iron Lore Entertainment | video game developer | October 2000 |
| John Hancock Insurance | business | 1862 |
| Massachusetts Bay Transportation Authority | public transport network, transport company | 1964 |
| New Balance | business, subsidiary company | 1906 |
| Reebok | business, enterprise | 1895 |
| Semrush | brand, business, public company | August 3, 2008 |
| Suffolk University | private not-for-profit educational institution, private university | 1906 |
| University of Massachusetts | state university system | 1863 |
| Vertex Pharmaceuticals | pharmaceutical company, organization, business, public company | 1989 |
| Vic Firth Company | business, musical instrument manufacturing company | 1963 |
| WHOOP | business | — |
| Ximian | business, enterprise | October 19, 1999 |